Alpha Pi Sigma was founded on March 10, 1990 at San Diego State University. The Beta Chapter was established on March 1, 1996 at California State Polytechnic University, Pomona. Then in March of 2000 the Gamma Chapter was established at California State Polytechnic University, San Luis Obispo and the Delta Chapter at University of California, Riverside.

Latina women from a variety of backgrounds came together to form an organization that would unite and support Latina women on each campus. The Ladies of Alpha Pi Sigma pride themselves in holding their education in highest regard. They believe that campus involvement, academics, leadership, and community service are methods to achieve success at the University level. Other objectives of the Sorority include promoting members academically, personally, and professionally.

Although Alpha Pi Sigma identifies itself as a Latina based sorority, it does not discriminate against any ethnic group and welcomes all women that are interested in the Alpha Pi Sigma experience. A central tenet of Alpha Pi Sigma is promoting unity amongst women interested in the Latino culture.

The following are the Formal Purposes which Alpha Pi Sigma have successfully maintained and will continue to preserve:

1. To encourage and promote the academic excellence of our members through the establishment of study groups, tutoring services, and mentoring.
2. To establish a scholarship fund to benefit members of the organization and/or transfer and high school students.
3. To inspire unity, friendship, and sisterhood among its members.
4. To promote and develop the attainment of leadership skills for its members in order to serve the organization and the Latino community.
5. To further the professional careers of its members through networking with professionals in the community.
6. To encourage cultural awareness and interest in helping the Latino Community through volunteer work.